There are four variations of this virus, the denv1, denv2, denv3 and denv4 subtypes. Fisiopatologia del dengue enfermedades y trastornos. Registered in more than 120 countries, it is considered a global epidemic, a. Dengue is the most prevalent arthropodborne viral disease in tropical and subtropical countries. Seguindo tal multiplicacao, tem inicio viremia, disseminandose por todo o organismo. Etiologia, patogenese e suas implicacoes a nivel global. The new clinical classifications are dengue and severe dengue.
Tres teorias mais conhecidas tentam explicar sua ocorrencia 1. Dengue is a viral disease that has become a major public health problem in brazil and the world. Dengue virus denv belongs to the flaviviridae family, it is transmitted by mosquitos of the aedes genus, which has a worldwide distribution. Como esta escrito no titulo desse post, iremos abordar agora a patogenia e fisiopatologia da dengue. Apos a picada do mosquito, iniciase a replicacao viral nas celulas estriadas, lisas, fibroblastos e linfonodos locais, a seguir ocorre a disseminacao do virus no organismo, infectando predominantemente celulas do sistema reticuloendotelial baco, figado e medula ossea. Coinfection with zika and dengue viruses in 2 patients.
Every year, dengue virus denv infections cause more than 50 million cases, 500,000 hospitalizations, and 12,500 deaths worldwide. May 18, 2016 this feature is not available right now. Randomized comparison of oxygen mask treatment vs nasal continuous positive airway pressure in dengue shock syndrome with acute respiratory failure. It is clinically manifested as a subclinical infection, with undifferentiated fever the socalled dengue fever, and in a small number of individuals the dengue hemorrhagic feverdengue shock syndrome. The man becomes infected through the bite of the female hematophagous mosquito aedesaegypti. A suscetibilidade em relacao a febre hemorragica da dengue fhd nao esta totalmente esclarecida. Aug 19, 2019 fisiopatologia del dengue pdf download.
This flavivirus is a single strand rna virus that after their translation and replication in host cells produces three structural and seven nonstructural. Chikv, arbovirus, virus spread, diagnosis, treatment and prevention. Severe dengue most commonly occurs among infants and patients with secondary dengue virus denv infections i. It is a rna virus, with tropism for multiple human cells, with a wellestablished and. Surprising new dengue virus throws a spanner in disease control efforts. It is a rna virus, with tropism for multiple human cells, with a wellestablished and studied viral cycle. Dengue and zika virus diagnostic testing for patients with. Fisiopatologia del dengue pdf has a functional interface that allows you to easily choose which sections of the registry to scour, including bunk file associations, junk help files, and faulty activex items.
In venezuela, the dengue virus serotypes 1, clwsico and 4 are endemic, they circulate simultaneously throughout the year in the largest cities 3however severe epidemics of dengue or dhf in venezuela have been shown to be the result of the introduction of dengue virus serotype 3 in 4. For patients with suspected dengue or zika virus disease, nucleic acid amplification tests naats are the. Denv belongs to the genus flavivirus and is transmitted by aedes spp. Dengue and zika viruses are closely related mosquitoborne flaviviruses with similar transmission cycles, distribution throughout the tropics and subtropics, and disease manifestations including fever, rash, myalgia, and arthralgia. The most widely cited hypothesis for this occurrence is antibody dependent enhancement ade of. Apos serem inoculados atraves da picada do mosquito, os virus do dengue fazem uma primeira replicacao em celulas musculares estriadas, lisas e fibroblastos, bem como em linfonodos locais. Aggressive management of dengue shock syndrome may decrease mortality fisiopatologiz learn more about amazon giveaway. Dengue virus denv is responsible for the clinical entity known as dengue that is a great concern for economy and public health of tropical countries. A fisiopatologia causada pelo virus da dengue arboviroses. Virus dengue 2 complejo formado por anticuerpo no neutralizante y virus dengue 2. In venezuela, the dengue virus serotypes 1, clwsico and 4 are endemic, they circulate simultaneously throughout the year in the largest cities 3however severe epidemics of dengue or dhf in venezuela have been shown to be the result of the introduction of dengue virus. Dengue virus and dengue pathophysiology part 2 youtube. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
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